SYSTANE® Lubricant Eye Drops works great during the day, but dry eye can also strike while you sleep. Luckily, for overnight dry eye protection, there's long-lasting SYSTANE® NIGHTTIME Lubricant Eye Ointment. Designed to keep your eyes lubricated and comfortable throughout the night, SYSTANE® NIGHTTIME creates a shield that locks in moisture to allow for healing. Available in 3.5 g preservative-free tubes of eye lubricant, SYSTANE® NIGHTTIME helps provide overnight relief, when it is impractical to apply eye drops.